Hoxa5 Promotes Adipose Differentiation via Increasing DNA Methylation Level and Inhibiting PKA/HSL Signal Pathway in Mice

Hoxa5 Promotes Adipose Differentiation via Increasing DNA Methylation Level and Inhibiting PKA/HSL Signal Pathway in Mice

Background/Aims: Impaired adipogenesis may be the underlying cause in the development of obesity and type II diabetes. Mechanistically, the family of Homeobox transcription factors is implicated in the regulation of adipocyte fate. Hoxa5 is highly expressed in adipocytes, and its mRNA expression is...

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Bibliographic Details
Main Authors: Weina Cao, Yatao Xu, Dan Luo, Muhammad Saeed, Chao Sun
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Hoxa5
Adipocytes
Differentiation
Methylation
PKA/HSL pathway
Online Access:https://www.karger.com/Article/FullText/487343

Internet

https://www.karger.com/Article/FullText/487343

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