The Effect of a Histone Deacetylase Inhibitor (AR-42) and Zoledronic Acid on Adult T-Cell Leukemia/Lymphoma Osteolytic Bone Tumors

Adult T-cell leukemia/lymphoma (ATL) is an intractable disease affecting nearly 4% of Human T-cell Leukemia Virus Type 1 (HTLV-1) carriers. Acute ATL has a unique interaction with bone characterized by aggressive bone invasion, osteolytic metastasis, and hypercalcemia. We hypothesized that dual tumo...

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Bibliographic Details
Main Authors: Said M. Elshafae, Nicole A. Kohart, Justin T. Breitbach, Blake E. Hildreth, Thomas J. Rosol
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/20/5066