Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA

Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA

Abstract Background Bone defects remain a challenge today. In addition to osteogenic activation, the crucial role of angiogenesis has also gained attention. In particular, vascular endothelial growth factor (VEGF) is likely to play a significant role in bone regeneration, not only to restore blood s...

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Bibliographic Details
Main Authors: Maorui Zhang, Yuta Fukushima, Kosuke Nozaki, Hideyuki Nakanishi, Jia Deng, Noriyuki Wakabayashi, Keiji Itaka
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Inflammation and Regeneration
Subjects:
Bone regeneration
Angiogenesis
mRNA medicine
Vascular endothelial growth factor
Runt-related transcription factor 2
Mandible bone defect
Online Access:https://doi.org/10.1186/s41232-023-00285-3

Internet

https://doi.org/10.1186/s41232-023-00285-3

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