A molecular evolution approach to study the roles of tropomyosin in fission yeast.

Tropomyosin, a coiled-coil protein that binds along the length of the actin filament, is a universal regulator of the actin cytoskeleton. We have taken a bioinformatics/proteomic approach to studying structure-function relationships in this protein. The presence of a single, essential tropomyosin ge...

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Bibliographic Details
Main Authors: Susanne Cranz-Mileva, Melissa C Pamula, Bipasha Barua, Brinda Desai, Yaejee Hannah Hong, Jacquelyn Russell, Richard Trent, Jianqiu Wang, Nancy C Walworth, Sarah E Hitchcock-DeGregori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3805550?pdf=render