Mechanism Underlying Metformin Action and Its Potential to Reduce Gastric Cancer Risk

Mechanism Underlying Metformin Action and Its Potential to Reduce Gastric Cancer Risk

Diabetes mellitus is associated with a high risk of developing gastric cancer (GC). Metformin, which is conventionally used to treat type 2 diabetes, induces AMP-activated protein kinase signaling and suppresses gluconeogenesis. Recent studies have reported that metformin is associated with benefici...

Full description

Bibliographic Details
Main Authors: Wen-Hsi Lan, Ting-Yu Lin, Jia-Ai Yeh, Chun-Lung Feng, Jun-Te Hsu, Hwai-Jeng Lin, Chia-Jung Kuo, Chih-Ho Lai
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
metformin
gastric cancer
diabetes mellitus
reactive oxygen species
microbiota
Online Access:https://www.mdpi.com/1422-0067/23/22/14163

Internet

https://www.mdpi.com/1422-0067/23/22/14163

Similar Items