Modeled small airways lung deposition of two fixed-dose triple therapy combinations assessed with in silico functional respiratory imaging

Abstract Background Small airways disease plays a key role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and is a major cause of obstruction; therefore, it is a critical pharmacotherapy target. This study evaluated lung deposition of two inhaled corticosteroid (ICS)/long-acting...

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Bibliographic Details
Main Authors: Omar Usmani, Grace Li, Jan De Backer, Hosein Sadafi, Libo Wu, Jonathan Marshall
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-023-02534-y