Neurogenesis, neurodegeneration, interneuron vulnerability and amyloid-β in the olfactory bulb of APP/PS1 mouse model of Alzheimer’s disease
Alzheimer´s disease is the most prevalent neurodegenerative disease, mostly idiopathic and with palliative treatment. Neuropathologically, it is characterized by intracellular neurofibrillary tangles of tau protein and extracellular plaques of amyloid β peptides. The relationship between Alzheimer’s...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-05-01
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Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00227/full |