Neurogenesis, neurodegeneration, interneuron vulnerability and amyloid-β in the olfactory bulb of APP/PS1 mouse model of Alzheimer’s disease

Alzheimer´s disease is the most prevalent neurodegenerative disease, mostly idiopathic and with palliative treatment. Neuropathologically, it is characterized by intracellular neurofibrillary tangles of tau protein and extracellular plaques of amyloid β peptides. The relationship between Alzheimer’s...

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Bibliographic Details
Main Authors: Carlos eDe La Rosa Prieto, Daniel Saiz Sanchez, Isabel eUbeda-banon, Alicia eFlores-Cuadrado, Alino eMartinez-Marcos
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00227/full