Serum opacity factor normalizes erythrocyte morphology in Scarb1−/− mice in an HDL-free cholesterol-dependent way

Serum opacity factor normalizes erythrocyte morphology in Scarb1−/− mice in an HDL-free cholesterol-dependent way

Compared with WT mice, HDL receptor-deficient (Scarb1−/−) mice have higher plasma levels of free cholesterol (FC)-rich HDL and exhibit multiple pathologies associated with a high mol% FC in ovaries, platelets, and erythrocytes, which are reversed by lowering HDL. Bacterial serum opacity factor (SOF)...

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Bibliographic Details
Main Authors: Ziyi Wang, Dedipya Yelamanchili, Jing Liu, Antonio M. Gotto, Jr., Corina Rosales, Baiba K. Gillard, Henry J. Pownall
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Lipid Research
Subjects:
cholesterol
HDLs
hyperalphalipoproteinemia
scavenger receptor class B member 1
atherosclerosis
erythrocyte morphology
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523001293

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http://www.sciencedirect.com/science/article/pii/S0022227523001293

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