SIX1 amplification modulates stemness and tumorigenesis in breast cancer

Abstract Background Sine oculis homeobox homolog 1 (SIX1) is a transcription factor that has recently been identified as a crucial regulator of embryonic development and tumorigenesis. SIX1 is upregulated in different types of tumors, including breast cancer. However, the role and mechanism of SIX1...

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Bibliographic Details
Main Authors: Liantao Guo, Faminzi Li, Hanqing Liu, Deguang Kong, Chuang Chen, Shengrong Sun
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-023-04679-2