Systemic immune profile in Prader-Willi syndrome: elevated matrix metalloproteinase and myeloperoxidase and reduced macrophage inhibitory factor

Systemic immune profile in Prader-Willi syndrome: elevated matrix metalloproteinase and myeloperoxidase and reduced macrophage inhibitory factor

Abstract Background Prader-Willi syndrome (PWS) is a rare genetic neurodevelopmental syndrome with highly increased risk of obesity and cardiovascular disease (CVD). Recent evidence suggests that inflammation is implicated in the pathogenesis. Here we investigated CVD related immune markers to shed...

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Bibliographic Details
Main Authors: Sigrun Hope, Terje Nærland, Svein Olav Kolset, Thor Ueland, Ole A. Andreassen, Marianne Nordstrøm
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Prader-Willi Syndrome
15q11-q13
Obesity
Inflammation
Cardiovascular
Extracellular matrix
Online Access:https://doi.org/10.1186/s13023-023-02730-5

Internet

https://doi.org/10.1186/s13023-023-02730-5

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