A Myosin II-Based Nanomachine Devised for the Study of Ca<sup>2+</sup>-Dependent Mechanisms of Muscle Regulation

The emergent properties of the array arrangement of the molecular motor myosin II in the sarcomere of the striated muscle, the generation of steady force and shortening, can be studied in vitro with a synthetic nanomachine made of an ensemble of eight heavy-meromyosin (HMM) fragments of myosin from...

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Bibliographic Details
Main Authors: Irene Pertici, Giulio Bianchi, Lorenzo Bongini, Vincenzo Lombardi, Pasquale Bianco
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/19/7372