Effects of Manipulating Circulating Bile Acid Concentrations on Postprandial GLP-1 Secretion and Glucose Metabolism After Roux-en-Y Gastric Bypass

Effects of Manipulating Circulating Bile Acid Concentrations on Postprandial GLP-1 Secretion and Glucose Metabolism After Roux-en-Y Gastric Bypass

BackgroundAltered bile acid (BA) turnover has been suggested to be involved in the improved glucose regulation after Roux-en-Y gastric bypass (RYGB), possibly via stimulation of GLP-1 secretion. We investigated the role of exogenous as well as endogenous BAs for GLP-1 secretion after RYGB by adminis...

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Bibliographic Details
Main Authors: Isabella Jonsson, Kirstine N. Bojsen-Møller, Viggo B. Kristiansen, Simon Veedfald, Nicolai J. Wewer Albrechtsen, Trine R. Clausen, Rune E. Kuhre, Jens F. Rehfeld, Jens J. Holst, Sten Madsbad, Maria S. Svane
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Endocrinology
Subjects:
bile acids
colesevelam
RYGB
Roux-en-Y gastric bypass
glucagon-like peptide 1
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.681116/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.681116/full

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