SOSSB1 and SOSSB2 mutually regulate protein stability through competitive binding of SOSSA
Abstract Human single-stranded DNA-binding protein homologs hSSB1 (SOSSB1) and hSSB2 (SOSSB2) make a vital impact on maintaining genome stability as the B subunits of the sensor of single-stranded DNA complex (SOSS). However, whether and how SOSSB1 and SOSSB2 modulate mutual expression is unclear. T...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-08-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01619-3 |