Heterogeneous brain region-specific responses to astrocytic mitochondrial DNA damage in mice

Heterogeneous brain region-specific responses to astrocytic mitochondrial DNA damage in mice

Abstract Astrocytes display context-specific diversity in their functions and respond to noxious stimuli between brain regions. Astrocytic mitochondria have emerged as key players in governing astrocytic functional heterogeneity, given their ability to dynamically adapt their morphology to regional...

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Bibliographic Details
Main Authors: Daniela A. Ayala, Anthony Matarazzo, Bonnie L. Seaberg, Misha Patel, Eliana Tijerina, Camryn Matthews, Gabriel Bizi, Ashton Brown, Alan Ta, Mendell Rimer, Rahul Srinivasan
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Scientific Reports
Subjects:
Astrocyte mitochondrial DNA
Calcium influx
Mitochondrial dynamics
Striatum
Hippocampus
Heterogenous
Online Access:https://doi.org/10.1038/s41598-024-69499-w

Internet

https://doi.org/10.1038/s41598-024-69499-w

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