Development of B cells and erythrocytes is specifically impaired by the drug celastrol in mice.

BACKGROUND:Celastrol, an active compound extracted from the root of the Chinese medicine "Thunder of God Vine" (Tripterygium wilfordii), exhibits anticancer, antioxidant and anti-inflammatory activities, and interest in the therapeutic potential of celastrol is increasing. However, describ...

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Bibliographic Details
Main Authors: Sophie Kusy, Eliver E B Ghosn, Leonore A Herzenberg, Christopher H Contag
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335785?pdf=render