Study protocol for Ketamine as an adjunctive therapy for major depression (2): a randomised controlled trial (KARMA-Dep [2])

Abstract Background Depression is a common psychiatric disorder and a leading cause of disability worldwide. Conventional monoaminergic antidepressants have limited efficacy and take weeks to exert a therapeutic effect. Single infusions of subanaesthetic doses of ketamine exhibit rapid antidepressan...

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Main Authors: Ana Jelovac, Cathal McCaffrey, Masashi Terao, Enda Shanahan, Enas Mohamed, Emma Whooley, Kelly McDonagh, Sarah McDonogh, Anna Igoe, Orlaith Loughran, Ellie Shackleton, Ciaran O’Neill, Declan M. McLoughlin
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-023-05365-9