New Insights into Cancer Targeted Therapy: Nodal and Cripto-1 as Attractive Candidates

New Insights into Cancer Targeted Therapy: Nodal and Cripto-1 as Attractive Candidates

The transforming growth factor beta (TGF-β) signaling is fundamental for correct embryonic development. However, alterations of this pathway have been correlated with oncogenesis, tumor progression and sustaining of cancer stem cells (CSCs). Cripto-1 (CR-1) and Nodal are two embryonic proteins invol...

Full description

Bibliographic Details
Main Authors: Paola Arboretto, Michele Cillo, Antonio Leonardi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
Nodal
Cripto-1
proliferation
drug resistance
biomarker
therapeutic targets
Online Access:https://www.mdpi.com/1422-0067/22/15/7838

Internet

https://www.mdpi.com/1422-0067/22/15/7838

Similar Items