Blood Levels of Free-Circulating Mitochondrial DNA in Septic Shock and Postsurgical Systemic Inflammation and Its Influence on Coagulation: A Secondary Analysis of a Prospective Observational Study

Blood Levels of Free-Circulating Mitochondrial DNA in Septic Shock and Postsurgical Systemic Inflammation and Its Influence on Coagulation: A Secondary Analysis of a Prospective Observational Study

Major surgery is regularly associated with clinical signs of systemic inflammation, which potentially affects the rapid identification of sepsis. Therefore, this secondary analysis of an observational study aims to determine whether NADH dehydrogenase 1 (ND1) mitochondrial DNA (mtDNA) could be used...

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Bibliographic Details
Main Authors: Emmanuel Schneck, Fabian Edinger, Matthias Hecker, Natascha Sommer, Oleg Pak, Norbert Weissmann, Andreas Hecker, Martin Reichert, Melanie Markmann, Michael Sander, Christian Koch
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Journal of Clinical Medicine
Subjects:
sepsis
DAMPs
SIRS
inflammation
coagulation
coagulopathy
Online Access:https://www.mdpi.com/2077-0383/9/7/2056

Internet

https://www.mdpi.com/2077-0383/9/7/2056

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