CellO: comprehensive and hierarchical cell type classification of human cells with the Cell Ontology

Summary: Cell type annotation is a fundamental task in the analysis of single-cell RNA-sequencing data. In this work, we present CellO, a machine learning-based tool for annotating human RNA-seq data with the Cell Ontology. CellO enables accurate and standardized cell type classification of cell clu...

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Bibliographic Details
Main Authors: Matthew N. Bernstein, Zhongjie Ma, Michael Gleicher, Colin N. Dewey
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422031110X