Genome-wide fine-mapping identifies pleiotropic and functional variants that predict many traits across global cattle populations

Genomic prediction of phenotype may be improved by using DNA mutations with functional, evolutionary, and pleiotropic consequences. Here the authors describe a method for genome-wide fine-mapping of QTLs and develop a genotyping array for improved prediction of genetic values for cattle traits.

Bibliographic Details
Main Authors: Ruidong Xiang, Iona M. MacLeod, Hans D. Daetwyler, Gerben de Jong, Erin O’Connor, Chris Schrooten, Amanda J. Chamberlain, Michael E. Goddard
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21001-0