Encapsulation of PI3K Inhibitor LY294002 within Polymer Nanoparticles Using Ion Pairing Flash Nanoprecipitation

Encapsulation of PI3K Inhibitor LY294002 within Polymer Nanoparticles Using Ion Pairing Flash Nanoprecipitation

Flash nanoprecipitation (FNP) is a turbulent mixing process capable of reproducibly producing polymer nanoparticles loaded with active pharmaceutical ingredients (APIs). The nanoparticles produced with this method consist of a hydrophobic core surrounded by a hydrophilic corona. FNP produces nanopar...

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Bibliographic Details
Main Authors: Austin D. Fergusson, Rui Zhang, Judy S. Riffle, Richey M. Davis
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
polymer nanoparticles
LY294002
flash nanoprecipitation
drug release
Online Access:https://www.mdpi.com/1999-4923/15/4/1157

Internet

https://www.mdpi.com/1999-4923/15/4/1157

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