Unveiling adcyap1 as a protective factor linking pain and nerve regeneration through single-cell RNA sequencing of rat dorsal root ganglion neurons

Unveiling adcyap1 as a protective factor linking pain and nerve regeneration through single-cell RNA sequencing of rat dorsal root ganglion neurons

Abstract Background Severe peripheral nerve injury (PNI) often leads to significant movement disorders and intractable pain. Therefore, promoting nerve regeneration while avoiding neuropathic pain is crucial for the clinical treatment of PNI patients. However, established animal models for periphera...

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Bibliographic Details
Main Authors: Qi Chen, Xi-Yin Zhang, Yu-Pu Wang, Yun-Jie Fu, Feng Cao, Yi-Nuo Xu, Jin-Ge Kong, Na-Xi Tian, Yu Xu, Yun Wang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Biology
Subjects:
Dorsal root ganglion
Neuropathic pain
Axon regeneration
Peripheral nerve injury
Single-cell RNA-seq
Online Access:https://doi.org/10.1186/s12915-023-01742-8

Internet

https://doi.org/10.1186/s12915-023-01742-8

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