Are cup-like blasts specific to AML patients with FLT3 ITD and a normal karyotype? An ALL case report and review of the literature

Are cup-like blasts specific to AML patients with FLT3 ITD and a normal karyotype? An ALL case report and review of the literature

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Cup-like morphology is defined as cup-like nuclear invagination spanning ≥25% of the nuclear diameter in >10% of blasts. Studies have shown that FLT3 ITD and normal cytology are strongly associated with cup-like morphology in acute myeloid leukemia (AML) patients. Herein we describe a patient wit...

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Bibliographic Details
Main Authors: Özgür Mehtap, Elif Birtaş Ateşoğlu, Emel Gönüllü, Hakan Keski, Abdullah Hacıhanefioğlu
Format: Article
Language:English
Published: Galenos Publishing House 2011-06-01
Series:Turkish Journal of Hematology
Subjects:
ALL
AML
cup-like blast
FLT3 ITD
Online Access:http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-57614

Internet

http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-57614

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