Solubility measurement and modeling of hydroxychloroquine sulfate (antimalarial medication) in supercritical carbon dioxide
Abstract A supercritical fluid, such as supercritical carbon dioxide (scCO2) is increasingly used for the micronization of pharmaceuticals in the recent past. The role of scCO2 as a green solvent in supercritical fluid (SCF) process is decided by the solubility information of the pharmaceutical comp...
Main Authors: | Gholamhossein Sodeifian, Chandrasekhar Garlapati, Maryam Arbab Nooshabadi, Fariba Razmimanesh, Amirmuhammad Tabibzadeh |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-34900-7 |
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