Establishing an hTERT-driven immortalized umbilical cord-derived mesenchymal stem cell line and its therapeutic application in mice with liver failure

Establishing an hTERT-driven immortalized umbilical cord-derived mesenchymal stem cell line and its therapeutic application in mice with liver failure

Acute liver failure (ALF) is characterized by rapid liver cell destruction. It is a multi-etiological and fulminant complication with a clinical mortality of over 80%. Therapy using mesenchymal stem cells (MSCs) or MSCs-derived exosomes can alleviate acute liver injury, which has been demonstrated i...

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Bibliographic Details
Main Authors: Qi Chen, Meixian Jin, Simin Wang, Kexin Wang, Liqin Chen, Xiaojuan Zhu, Ying Zhang, Yi Wang, Yang Li, Shao Li, Youmin Zeng, Lei Feng, Wanren Yang, Yi Gao, Shuqin Zhou, Qing Peng
Format: Article
Language:English
Published: SAGE Publishing 2023-09-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314231200328

Internet

https://doi.org/10.1177/20417314231200328

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