Could Dampening Expression of the <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content> <italic toggle="yes">mtrCDE</italic>-Encoded Efflux Pump Be a Strategy To Preserve Currently or Resurrect Formerly Used Antibiotics To Treat Gonorrhea?

Could Dampening Expression of the <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content> <italic toggle="yes">mtrCDE</italic>-Encoded Efflux Pump Be a Strategy To Preserve Currently or Resurrect Formerly Used Antibiotics To Treat Gonorrhea?

ABSTRACT Neisseria gonorrhoeae has developed resistance to every antibiotic introduced for treatment of gonorrhea since 1938, and concern now exists that gonorrheal infections may become refractory to all available antibiotics approved for therapy. The current recommended dual antibiotic treatment r...

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Bibliographic Details
Main Authors: Shaochun Chen, Kristie L. Connolly, Corinne Rouquette-Loughlin, Alexander D’Andrea, Ann E. Jerse, William M. Shafer
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mBio
Subjects:
Neisseria gonorrhoeae
efflux pumps
penicillin
transcriptional regulation
Online Access:https://journals.asm.org/doi/10.1128/mBio.01576-19

Internet

https://journals.asm.org/doi/10.1128/mBio.01576-19

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