Early-life house dust mite aeroallergen exposure augments cigarette smoke-induced myeloid inflammation and emphysema in mice

Early-life house dust mite aeroallergen exposure augments cigarette smoke-induced myeloid inflammation and emphysema in mice

Abstract Background Longitudinal studies have identified childhood asthma as a risk factor for obstructive pulmonary disease (COPD) and asthma-COPD overlap (ACO) where persistent airflow limitation can develop more aggressively. However, a causal link between childhood asthma and COPD/ACO remains to...

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Bibliographic Details
Main Authors: Nok Him Fung, Quynh Anh Nguyen, Catherine Owczarek, Nick Wilson, Nadeem Elahee Doomun, David De Souza, Kylie Quinn, Stavros Selemidis, Jonathan McQualter, Ross Vlahos, Hao Wang, Steven Bozinovski
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Respiratory Research
Subjects:
Asthma
COPD
ACO
MMP-12
Macrophages
Emphysema
Online Access:https://doi.org/10.1186/s12931-024-02774-6

Internet

https://doi.org/10.1186/s12931-024-02774-6

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