Paradoxical Acceleration of Dithiothreitol-Induced Aggregation of Insulin in the Presence of a Chaperone
The kinetics of dithiothreitol (DTT)-induced aggregation of human recombinant insulin and the effect of α-crystallin, a representative of the family of small heat shock proteins, on the aggregation process have been studied using dynamic light scattering technique. Analysis of the distribution of th...
Main Authors: | Boris Kurganov, Konstantin Muranov, Natalya Artemova, Bella Gurvits, Zoya Bumagina |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-11-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/11/11/4556/ |
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