Targeting Glutamine Metabolism in Prostate Cancer

Targeting Glutamine Metabolism in Prostate Cancer

Glutamine is a conditionally essential amino acid important for cancer cell proliferation through intermediary metabolism leading to de novo synthesis of purine and pyrimidine nucleotides, hexosamine biosytnehsis, fatty acid synthesis through reductive carboxylation, maintenance of redox homeostasis...

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Bibliographic Details
Main Authors: Neil Bhowmick, Edwin Posadas, Leigh Ellis, Stephen J Freedland, Dolores Di Vizio, Michael R Freeman, Dan Theodorescu, Robert Figlin, Jun Gong
Format: Article
Language:English
Published: IMR Press 2023-01-01
Series:Frontiers in Bioscience-Elite
Subjects:
glutamine
prostate cancer
glutaminase
myc
androgen receptor
mtor
castrate-resistance
pten
Online Access:https://www.imrpress.com/journal/FBE/15/1/10.31083/j.fbe1501002

Internet

https://www.imrpress.com/journal/FBE/15/1/10.31083/j.fbe1501002

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