Payload Delivery: Engineering Immune Cells to Disrupt the Tumour Microenvironment

Although chimeric antigen receptor (CAR) T cells have shown impressive clinical success against haematological malignancies such as B cell lymphoma and acute lymphoblastic leukaemia, their efficacy against non-haematological solid malignancies has been largely disappointing. Solid tumours pose many...

Full description

Bibliographic Details
Main Authors: Daniel Fowler, Callum Nattress, Alba Southern Navarrete, Marta Barisa, Jonathan Fisher
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/23/6000