mTOR Contributes to the Proteome Diversity through Transcriptome-Wide Alternative Splicing

mTOR Contributes to the Proteome Diversity through Transcriptome-Wide Alternative Splicing

The mammalian target of rapamycin (mTOR) pathway is crucial in energy metabolism and cell proliferation. Previously, we reported transcriptome-wide 3′-untranslated region (UTR) shortening by alternative polyadenylation upon mTOR activation and its impact on the proteome. Here, we further interrogate...

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Bibliographic Details
Main Authors: Sze Cheng, Naima Ahmed Fahmi, Meeyeon Park, Jiao Sun, Kaitlyn Thao, Hsin-Sung Yeh, Wei Zhang, Jeongsik Yong
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
mTOR signaling
alternative splicing
post-transcriptional gene regulation
functional proteome
Online Access:https://www.mdpi.com/1422-0067/23/20/12416

Internet

https://www.mdpi.com/1422-0067/23/20/12416

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