The Study of Cyclosporin A Nanocrystals Uptake and Transport across an Intestinal Epithelial Cell Model

Cyclosporin A nanocrystals (CsA-NCs) interaction with Caco-2 cells were investigated in this study, including cellular uptake and transport across Caco-2 cell monolayers. CsA-NCs of 165 nm, 240 nm and 450 nm were formulated. The dissolution of CsA-NCs was investigated by paddle method. The effect of...

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Bibliographic Details
Main Authors: Wenjun Sun, Yang Tian, Zengming Wang, Hui Zhang, Aiping Zheng
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/14/10/1975