Diagnostic Aqueous Humor Proteome Predicts Metastatic Potential in Uveal Melanoma

Diagnostic Aqueous Humor Proteome Predicts Metastatic Potential in Uveal Melanoma

Gene expression profiling (GEP) is clinically validated to stratify the risk of metastasis by assigning uveal melanoma (UM) patients to two highly prognostic molecular classes: class 1 (low metastatic risk) and class 2 (high metastatic risk). However, GEP requires intraocular tumor biopsy, which is...

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Bibliographic Details
Main Authors: Chen-Ching Peng, Shreya Sirivolu, Sarah Pike, Mary E. Kim, Bibiana Reiser, Hong-Tao Li, Gangning Liang, Liya Xu, Jesse L. Berry
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
uveal melanoma
proteomics
aqueous humor
biomarkers
ocular liquid biopsy
ocular cancer
Online Access:https://www.mdpi.com/1422-0067/24/7/6825

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https://www.mdpi.com/1422-0067/24/7/6825

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