Cytokine Receptor Endocytosis: New Kinase Activity-Dependent and -Independent Roles of PI3K

Type I and II cytokine receptors are cell surface sensors that bind cytokines in the extracellular environment and initiate intracellular signaling to control processes such as hematopoiesis, immune function, and cellular growth and development. One key mechanism that regulates signaling from cytoki...

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Bibliographic Details
Main Authors: Lily Jun-shen Huang, Ping-hung Chen, Huiyu Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00078/full