Plasmid-DNA Delivery by Covalently Functionalized PEI-SPIONs as a Potential ‘Magnetofection’ Agent

Plasmid-DNA Delivery by Covalently Functionalized PEI-SPIONs as a Potential ‘Magnetofection’ Agent

Nanoformulations for delivering nucleotides into cells as vaccinations as well as treatment of various diseases have recently gained great attention. Applying such formulations for a local treatment strategy, e.g., for cancer therapy, is still a challenge, for which improved delivery concepts are ne...

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Bibliographic Details
Main Authors: René Stein, Felix Pfister, Bernhard Friedrich, Pascal-Raphael Blersch, Harald Unterweger, Anton Arkhypov, Andriy Mokhir, Mikhail Kolot, Christoph Alexiou, Rainer Tietze
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
superparamagnetic iron oxide nanoparticles (SPIONs)
surface functionalization
ligand exchange
plasmid-DNA
magnetofection
transfection
Online Access:https://www.mdpi.com/1420-3049/27/21/7416

Internet

https://www.mdpi.com/1420-3049/27/21/7416

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