Expression of Phosphorylated BRD4 Is Markedly Associated with the Activation Status of the PP2A Pathway and Shows a Strong Prognostic Value in Triple Negative Breast Cancer Patients

Expression of Phosphorylated BRD4 Is Markedly Associated with the Activation Status of the PP2A Pathway and Shows a Strong Prognostic Value in Triple Negative Breast Cancer Patients

The bromodomain-containing protein 4 (BRD4), a member of the bromodomain and extra-terminal domain (BET) protein family, has emerged in the last years as a promising molecular target in many tumors including breast cancer. The triple negative breast cancer (TNBC) represents the molecular subtype wit...

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Bibliographic Details
Main Authors: Marta Sanz-Álvarez, Ion Cristóbal, Melani Luque, Andrea Santos, Sandra Zazo, Juan Madoz-Gúrpide, Cristina Caramés, Cheng-Ming Chiang, Jesús García-Foncillas, Pilar Eroles, Joan Albanell, Federico Rojo
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
pBRD4
SET
PP2A
prognosis
triple negative breast cancer
Online Access:https://www.mdpi.com/2072-6694/13/6/1246

Internet

https://www.mdpi.com/2072-6694/13/6/1246

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