Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.

The identification of sensitive biomarkers for the detection of ovarian cancer is of high clinical relevance for early detection and/or monitoring of disease recurrence. We developed a systematic multi-step biomarker discovery and verification strategy to identify candidate DNA methylation markers f...

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Bibliographic Details
Main Authors: Mihaela Campan, Melissa Moffitt, Sahar Houshdaran, Hui Shen, Martin Widschwendter, Günter Daxenbichler, Tiffany Long, Christian Marth, Ite A Laird-Offringa, Michael F Press, Louis Dubeau, Kimberly D Siegmund, Anna H Wu, Susan Groshen, Uma Chandavarkar, Lynda D Roman, Andrew Berchuck, Celeste L Pearce, Peter W Laird
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3233546?pdf=render