Albiflorin ameliorates thioacetamide-induced hepatic fibrosis: The involvement of NURR1-mediated inflammatory signaling cascades in hepatic stellate cells activation

Albiflorin ameliorates thioacetamide-induced hepatic fibrosis: The involvement of NURR1-mediated inflammatory signaling cascades in hepatic stellate cells activation

Thioacetamide (TAA) within the liver generates hepatotoxic metabolites that can be induce hepatic fibrosis, similar to the clinical pathological features of chronic human liver disease. The potential protective effect of Albiflorin (ALB), a monoterpenoid glycoside found in Paeonia lactiflora Pall, a...

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Bibliographic Details
Main Authors: Jian Song, Bo-Feng Qin, Qi-Yuan Feng, Jin-Jin Zhang, Gui-Yun Zhao, Zheng Luo, Hai-Ming Sun
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Thioacetamide
Albiflorin
Hepatic fibrosis
NURR1
P2×7r
Online Access:http://www.sciencedirect.com/science/article/pii/S014765132400410X

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http://www.sciencedirect.com/science/article/pii/S014765132400410X

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