Improving In Vivo Brain Delivery of Monoclonal Antibody Using Novel Cyclic Peptides

Many proteins can be used to treat brain diseases; however, the presence of the blood−brain barrier (BBB) creates an obstacle to delivering them into the brain. Previously, various molecules were delivered through the paracellular pathway of the BBB via its modulation, using ADTC5 and HAV6...

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Bibliographic Details
Main Authors: Kavisha R. Ulapane, Brian M. Kopec, Teruna J. Siahaan
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/11/11/568