Mitochondrial antioxidant SkQ1 decreases inflammation following hemorrhagic shock by protecting myocardial mitochondria

Mitochondrial antioxidant SkQ1 decreases inflammation following hemorrhagic shock by protecting myocardial mitochondria

Background: Hemorrhagic shock (HS) is a type of hypovolemic shock characterized by hemodynamic instability, tissue hypoperfusion and cellular hypoxia. In pathophysiology, the gradual accumulation of reactive oxygen species (ROS) damages the mitochondria, leading to irreversible cell damage and the r...

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Bibliographic Details
Main Authors: Bo Jia, Jingjing Ye, Lebin Gan, Rui Li, Mengwei Zhang, Diya Sun, Lin Weng, Yufei Xiong, Jun Xu, Peng Zhang, Wei Huang, Ming Zheng, Tianbing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Physiology
Subjects:
hemorrhagic shock
SkQ1
mitochondria
inflammatory response
MTDs
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.1047909/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.1047909/full

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