Human NK cells confer protection against HIV-1 infection in humanized mice

The role of NK cells against HIV-1 infections remains to be elucidated in vivo. While humanized mouse models potentially could be used to directly evaluate human NK cell responses during HIV-1 infection, improved functional development of human NK cells in these hosts is needed. Here, we report the...

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Bibliographic Details
Main Authors: Can M. Sungur, Qiankun Wang, Ayşe N. Ozantürk, Hongbo Gao, Aaron J. Schmitz, Marina Cella, Wayne M. Yokoyama, Liang Shan
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-12-01
Series:The Journal of Clinical Investigation
Subjects:
Online Access:https://doi.org/10.1172/JCI162694