Etiology-Specific Remodeling in Ventricular Tissue of Heart Failure Patients and Its Implications for Computational Modeling of Electrical Conduction

With an estimated 64.3 million cases worldwide, heart failure (HF) imposes an enormous burden on healthcare systems. Sudden death from arrhythmia is the major cause of mortality in HF patients. Computational modeling of the failing heart provides insights into mechanisms of arrhythmogenesis, risk st...

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Bibliographic Details
Main Authors: Aparna C. Sankarankutty, Joachim Greiner, Jean Bragard, Joseph R. Visker, Thirupura S. Shankar, Christos P. Kyriakopoulos, Stavros G. Drakos, Frank B. Sachse
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.730933/full