Alendronate reduces periosteal microperfusion in vivo

Alendronate reduces periosteal microperfusion in vivo

Objectives: Bisphosphonates are known to induce a severe adverse effect known as medication-related osteonecrosis of the jaw (MRONJ). Previous studies have proven the impact of bisphosphonates on microperfusion; therefore, this study aimed to investigate alendronate-induced microcirculatory reaction...

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Bibliographic Details
Main Authors: Danielle N. Kundert, Frank Tavassol, Andreas Kampmann, Nils-Claudius Gellrich, Daniel Lindhorst, Marc M. Precht, Paul Schumann
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Heliyon
Subjects:
Bisphosphonates
MRONJ
Microcirculation
Intravital fluorescence microscopy
Lewis rats
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023066768

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http://www.sciencedirect.com/science/article/pii/S2405844023066768

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