Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells
Rore et al generate testicular somatic cell-like cells (TesLCs) including Sertoli cell-like cells from mouse embryonic stem cells in xeno-free culture. They created testicular organoids in aggregation co-culture of TesLCs and epiblast-like cells (EpiLCs) and also find that TesLC-conditioned media pr...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-06-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02322-8 |