A simple LC-MS/MS method for pharmacokinetic study of carvedilol and 4/-hydroxyphenyl carvedilol at a low dose

A simple LC-MS/MS method for pharmacokinetic study of carvedilol and 4/-hydroxyphenyl carvedilol at a low dose

Background and purpose: The study was aimed at validating a simple, rapid, and low-cost LC-MS/MS method for carvedilol and 4/-hydroxyphenyl carvedilol assay in human plasma. The validated method was applied to investigate the pharmacokinetics after a low dose of 6.25 mg. carvedilol. Experimental app...

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Bibliographic Details
Main Authors: Wanna Eiamart, Nantaporn Prompila, Yaowatree Jumroen, Nonlanee Sayankuldilok, Pajaree Chariyavilaskul, Supeecha Wittayalertpanya
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
carvedilol; 4-hydroxyphenyl carvedilol; pharmacokinetics; tandem mass spectrometry
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2022;volume=17;issue=3;spage=231;epage=241;aulast=Eiamart

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2022;volume=17;issue=3;spage=231;epage=241;aulast=Eiamart

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