A continuously efficient O2-supplying strategy for long-term modulation of hypoxic tumor microenvironment to enhance long-acting radionuclides internal therapy

A continuously efficient O2-supplying strategy for long-term modulation of hypoxic tumor microenvironment to enhance long-acting radionuclides internal therapy

Abstract Radionuclides internal radiotherapy (RIT) is a clinically powerful method for cancer treatment, but still poses unsatisfactory therapeutic outcomes due to the hypoxic characteristic of tumor microenvironment (TME). Catalase (CAT) or CAT-like nanomaterials can be used to enzymatically decomp...

Full description

Bibliographic Details
Main Authors: Jingchao Li, Tingting Wang, Yuanfei Shi, Zichen Ye, Xun Zhang, Jiang Ming, Yafei Zhang, Xinyan Hu, Yun Li, Dongsheng Zhang, Qianhe Xu, Jun Yang, Xiaolan Chen, Nian Liu, Xinhui Su
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Nanobiotechnology
Subjects:
Radionuclides internal therapy
Pd-based nanomaterials
Continuous hypoxia relief
Moderate NIR-II photothermal therapy
Online Access:https://doi.org/10.1186/s12951-023-02268-5

Internet

https://doi.org/10.1186/s12951-023-02268-5

Similar Items