Mouse T-cells restrict replication of human immunodeficiency virus at the level of integration

<p>Abstract</p> <p>Background</p> <p>The development of an immunocompetent, genetically modified mouse model to study HIV-1 pathogenesis and to test antiviral strategies has been hampered by the fact that cells from native mice do not or only inefficiently support sever...

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Bibliographic Details
Main Authors: Goffinet Christine, Tervo Hanna-Mari, Keppler Oliver T
Format: Article
Language:English
Published: BMC 2008-07-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/58