Identification and characterization of a first-generation inhibitor of claudin-1 in colon cancer progression and metastasis

Identification and characterization of a first-generation inhibitor of claudin-1 in colon cancer progression and metastasis

Colorectal cancer (CRC) is a leading cause of the cancer-related deaths worldwide. Thus, developing novel and targeted therapies for inhibiting CRC progression and metastasis is urgent. Several studies, including ours, have reported a causal role for an upregulated claudin-1 expression in promoting...

Full description

Bibliographic Details
Main Authors: Iram Fatima, Jaya Prakash Uppada, Yashpal S. Chhonker, Saiprasad Gowrikumar, Susmita Barman, Sourav Roy, Kirsten T. Tolentino, Nicholas Palermo, Amar Natarajan, Daniel R. Beauchamp, Alex Vecchio, Daryl J. Murry, Amar B. Singh, Corey R. Hopkins, Punita Dhawan
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Claudin-1
Colon cancer
Src
Chemoresistance
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223000434

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223000434

Similar Items