Tanshinone IIA alters the transforming growth factor-1/Smads pathway in angiotensin II-treated rat hepatic stellate cells

Objective To investigate the effects of tanshinone IIA on the transforming growth factor-β1 (TGF-β1)/Smads signaling pathway in angiotensin II-treated hepatic stellate cells (HSCs). Methods HSCs were cultured and treated with angiotensin II (10 μM) or angiotensin II (10 μM) plus tanshinone IIA (3, 1...

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Bibliographic Details
Main Authors: Guo-wei Wei, Ke-yue Li, Ke-li Tang, Cheng-Xian Shi
Format: Article
Language:English
Published: SAGE Publishing 2020-06-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060520926358