In silico design of two novel fusion proteins, p28-IL-24 and p28-M4, targeted to breast cancer cells

Background and purpose: An anticancer peptide P28, has shown to be cytolethal on various cancer cells including breast cancer. Moreover, p28 can be alsoused as a targeting moiety in the structure of fusion proteins. IL-24 (or its truncated form, M4) is a cytokine with anticancer activity against a w...

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Bibliographic Details
Main Authors: Reza Ghavimi, Elmira Mohammadi, Vajihe Akbari, Fatemeh Shafiee, Ali Jahanian-Najafabadi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2020;volume=15;issue=2;spage=200;epage=208;aulast=Ghavimi